Bisdemethoxycurcumin
Cat. No.：YN270435
CAS No. ：33171-05-0
| 产品名称: | Bisdemethoxycurcumin |
| CAS No.: | 33171-05-0 |
| Chemical Name: | 1,7-bis(4-hydroxyphenyl)-1E,6E-heptadiene-3,5-dione |
| Synonyms: | 双去甲氧基姜黄素; Curcumin III; Didemethoxycurcumin |
| 分子量: | 308.33 |
| 分子式: | C₁₉H₁₆O₄ |
| SMILES: | O=C(CC(/C=C/C1=CC=C(O)C=C1)=O)/C=C/C2=CC=C(O)C=C2.[(E)].[(E)] |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | 双去甲氧基姜黄素(Bisdemethoxycurcumin)是姜黄素衍生物，具有抗炎症和抗癌活性。 |
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Fiala, M., Liu, P.T., Espinosa-Jeffrey, A., et al.Innate immunity and transcription of MGAT-III and Toll-like receptors in Alzheimer's disease patients are improved by bisdemethoxycurcuminProc. Natl. Acad. Sci. USA104(31),12849-12854(2007)
Masoumi, A., Goldenson, B., Ghirmai, S., et al.1α,25-dihydroxyvitamin D3 interacts with curcuminoids to stimulate amyloid-β clearance by macrophages of Alzheimer's disease patientsJ. Alzheimers Dis.17(3),703-717(2009)
Cashman, J.R., Fhirmai, S., Abel, K.J., et al.Immune defects in Alzheimer's disease: New medications developmentBMC Neurosci.9(Suppl2),S13(2008)
Sandur, S.K., Pandley, M.K., Ahn, K.S., et al.Curcumin, demethoxycurcumin, bisdemethoxycurcumin, tetrahydrocurcumin and turmerones differentially regulate anti-inflammatory and anti-proliferative responses through a ROS-independent mechanismCarcinogenesis28(8),1765-1773(2007)
Basile, V., Ferrari, E., Lazzari, S., et al.Curcumin derivatives: Molecular basis of their anti-cancer activityBiochem. Pharmacol.78(10),1305-1315(2009)
Ryu, M.J., Cho, M., Song, J.Y., et al.Natural derivatives of curcumin attenuate the Wnt/β-catenin pathway through down-regulation of the transcriptional coactivator p300Biochem. Biophys. Res. Commun.377(4),1304-1308(2008)
Mahattanadul, S., Nakamura, T., Panichayupakaranant, P., et al.Comparative antiulcer effect of bisdemethoxycurcumin and curcumin in a gastric ulcer model systemPhytomedicine16(4),342-351(2009)
