Fraxetin
Cat. No.：YN270470
CAS No. ：574-84-5
规格
价格(RMB)
库存
| 产品名称: | Fraxetin |
| CAS No.: | 574-84-5 |
| Chemical Name: | 7,8-dihydroxy-6-methoxy-2H-1-benzopyran-2-one |
| Synonyms: | 弗拉西汀 |
| 分子量: | 208.17 |
| 分子式: | C₁₀H₈O₅ |
| SMILES: | O=C1C=CC2=CC(OC)=C(O)C(O)=C2O1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Fraxetin 是从Cortex Fraxini中分离出来的。 Fraxetin 具有抗肿瘤，抗氧化作用和抗炎作用。 Fraxetin 诱导细胞凋亡 (apoptosis)。 |
| IC50和靶点: | |
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Wu, C.-R., Huang, M.-Y., Lin, Y.-T., et al.Antioxidant properties of Cortex Fraxini and its simple coumarinsFood Chem.104(4),1464-1471(2007)
Zhang, Y., Wang, L., Deng, Y., et al.Fraxetin suppresses proliferation of non-small-cell lung cancer cells via preventing activation of signal transducer and activator of transcription 3Tohoku J. Exp. Med.248(1),3-12(2019)
Wu, B., Wang, R., Li, S., et al.Antifibrotic effects of fraxetin on carbon tetrachloride-induced liver fibrosis by targeting NF-κB/IκBα, MAPKs and Bcl-2/Bax pathwaysPharmacol. Rep.71(3),409-416(2019)
