Levistolide A
Cat. No.：YN270498
CAS No. ：88182-33-6
| 产品名称: | Levistolide A |
| CAS No.: | 88182-33-6 |
| Chemical Name: | (1Z,5S,5aS,8Z,10bS,10cS)-1,8-dibutylidene-5,5a,6,7,8,10b-hexahydro-1H-5,10c-ethanonaphtho[1,2-c:7,8-c′]difuran-3,10-dione |
| Synonyms: | Diligustilide,欧当归内酯A,Levistilide A |
| 分子量: | 380.48 |
| 分子式: | C₂₄H₂₈O₄ |
| SMILES: | O=C(O/C([C@@]1(CC2)[C@]34[H])=C\CCC)C1=C[C@]2([H])[C@]3([H])CCC5=C4C(O/C5=C\CCC)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Levistolide A 是一种从传统中药川芎中分离出来的天然化合物，用于研究癌症。 Levistolide A 可以通过 ROS 介导的内质网应激诱导凋亡。 |
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Choi, H.G., Je, I.-G., Kim, G.J., et al.Chemical constituents of the root of Angelica tenuissima and their anti-allergic inflammatory activityNat. Prod. Commun.12(5),779-780(2017)
Yang, Y., Zhang, Y., Wang, L., et al.Levistolide A induces apoptosis via ROS-mediated ER stress pathway in colon cancer cellsCell. Physiol. Biochem.42(3),929-938(2017)
Velázquez-Moyado, J.A., Martínez-González, A., Linares, E., et al.Gastroprotective effect of diligustilide isolated from roots of Ligusticum porteri coulter & rose (Apiaceae) on ethanol-induced lesions in ratsJ. Ethnopharmacol.174,403-409(2015)
Qu, X., Guan, P., Han, L., et al.Levistolide A attenuates Alzheimer's pathology through activation of the PPARγ pathwayNeurotherapeutics18(1),326-339(2021)
