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3-​O-​Acetyloleanolic acid

Cat. No.:YN270531

  • CAS No. :4339-72-4

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    • 参考文献
    • 产品名称: 3-​O-​Acetyloleanolic acid
      CAS No.: 4339-72-4
      Chemical Name: 3β-(acetyloxy)-olean-12-en-28-oic acid
      Synonyms:齐墩果酸3-乙酸酯
      分子量:498.74
      分子式:C₃₂H₅₀O₄
      SMILES:C[C@]12[C@]3(C([C@@]4([H])[C@](C(O)=O)(CCC(C)(C)C4)CC3)=CC[C@]1([H])[C@@]5([C@@](C(C)([C@@H](OC(C)=O)CC5)C)([H])CC2)C)C
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: 3-O-Acetyloleanolic acid (3AOA) 是从Vigna sinensisK. 种子中提取得到的一种齐墩果醇酸,可诱导癌细胞凋亡并拥有抗血管生成作用。
      IC50和靶点:
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    • Kim, N.-C., Desjardins, A.E., Wu, C.D., et al.Activity of triterpenoid glycosides from the root bark of Mussaenda macrophylla against two oral pathogensJ. Nat. Prod.62(10),1379-1384(1999)

      Yoo, K.H., Park, J.-H., Cui, E.J., et al.3-O-acetyloleanolic acid induces apoptosis in human colon carcinoma HCT-116 cellsPhytother. Res.26(10),1541-1546(2012)

      Cui, E.-J., Hwang-Bo, J., Park, J.-H., et al.3-O-Acetyloleanolic acid exhibits anti-angiogenic effects and induces apoptosis in human umbilical vein endothelial cellsBiotechnol. Lett.35(11),1807-1815(2013)

      Choi, J.K., Oh, H.-M., Lee, S., et al.Oleanolic acid acetate inhibits atopic dermatitis and allergic contact dermatitis in a murine modelToxicol. Appl. Pharmacol.269(1),72-80(2013)

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