Vinblastine sulfate
Cat. No.：YN280069
CAS No. ：143-67-9
| 产品名称: | Vinblastine sulfate |
| CAS No.: | 143-67-9 |
| Chemical Name: | vincaleukoblastine, monosulfate |
| Synonyms: | 硫酸长春碱; Vincaleukoblastine sulfate salt |
| 分子量: | 909.05 |
| 分子式: | C₄₆H₆₀N₄O₁₃S |
| SMILES: | [H][C@@]12C[C@@](C3=C(OC)C=C(N([C@]4([H])[C@@]56[C@]7([H])[C@](C=CCN7CC6)(CC)[C@@H](OC(C)=O)[C@@]4(C(OC)=O)O)C)C5=C3)(C(OC)=O)C(NC8=C9C=CC=C8)=C9CC[N@](C2)C[C@](O)(CC)C1.OS(=O)(O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Vinblastine sulfate是一种针对各种癌症类型的有细胞毒性的生物碱。 长春花碱可抑制微管的形成，抑制nAChR的IC50值为8.9 μM。 |
| IC50和靶点: | |
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Jordan, M.A., Himes, R.H., and Wilson, L.Comparison of the effects of vinblastine, vincristine, vindesine, and vinepidine on microtubule dynamics and cell proliferation in vitroCancer Res.45(6),2741-2747(1985)
Martinelli, G., Cocorocchio, E., Saletti, P.C., et al.Efficacy of vinblastine, bleomycin, methotrexate (VBM) combination chemotherapy with involved field radiotherapy in early stage (I-IIA) Hodgkin disease patientsLeuk. Lymphoma44(11),1919-1923(2003)
