IU1
Cat. No.:YN280071
CAS No. :314245-33-5
产品名称: | IU1 |
CAS No.: | 314245-33-5 |
Chemical Name: | 1-[1-(4-fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(1-pyrrolidinyl)-ethanone |
Synonyms: | IU1;Vismodegib (GDC-0449);1-(1-(4-fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl)-2-(pyrrolidin-1-yl)ethanone;1-[1-(4-FLUOROPHENYL)-2,5-DIMETHYL-1H-PYRROL-3-YL]-2-(1-PYRROLIDINYL)ETHANONE;AC1LDUCV;AC1Q2HNB;CHEMBL1410015;F1142-1244;SureCN6923146;Usp14 inhibitor |
分子量: | 300.37 |
分子式: | C₁₈H₂₁FN₂O |
SMILES: | CC1=CC(C(CN2CCCC2)=O)=C(C)N1C3=CC=C(F)C=C3 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | IU1 是一种特异性的Usp14抑制剂,IC50为 4-5 μM。 |
IC50和靶点: | |
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In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Lee, B.H., Lee, M.J., Park, S., et al.Enhancement of proteasome activity by a small-molecule inhibitor of USP14Nature467,179-184(2010)