Cabazitaxel
Cat. No.：YN280082
CAS No. ：183133-96-2
| 产品名称: | Cabazitaxel |
| CAS No.: | 183133-96-2 |
| Chemical Name: | β-[[(1,1-dimethylethoxy)carbonyl]amino]-α-hydroxy-benzenepropanoic acid, (αR,βS)-(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-11-hydroxy-4,6-dimethoxy-4a,8,13,13-tetramethyl-5-oxo-7,11-m |
| Synonyms: | XRP6258; RPR-116258A; taxoid XRP6258 |
| 分子量: | 835.93 |
| 分子式: | C₄₅H₅₇NO₁₄ |
| SMILES: | CC1=C([C@@H](OC)C([C@@]2(C)[C@@]3([H])[C@](OC(C)=O)(CO4)[C@H]4C[C@@H]2OC)=O)C(C)(C)[C@@]([C@H]3OC(C5=CC=CC=C5)=O)(O)C[C@@H]1OC([C@H](O)[C@H](C6=CC=CC=C6)NC(OC(C)(C)C)=O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Cabazitaxel 是天然紫杉烷脱乙酰基巴卡丁III 的半合成衍生物，具有显著的抗肿瘤功效。 |
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Vrignaud, P., Sémiond, D., Lejeune, P., et al.Preclinical antitumor activity of cabazitaxel, a semisynthetic taxane active in taxane-resistant tumors.Clin. Cancer Res.19(11),2973-2983(2013)
