Briciclib
Cat. No.:YN280090
CAS No. :865783-99-9
产品名称: | Briciclib |
CAS No.: | 865783-99-9 |
Chemical Name: | 2-methoxy-5-[[[(1E)-2-(2,4,6-trimethoxyphenyl)ethenyl]sulfonyl]methyl]-phenol 1-(dihydrogen phosphate) |
Synonyms: | ON 014185 |
分子量: | 474.42 |
分子式: | C₁₉H₂₃O₁₀PS |
SMILES: | O=S(CC1=CC(OP(O)(O)=O)=C(OC)C=C1)(/C=C/C2=C(OC)C=C(OC)C=C2OC)=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Briciclib 是一种可溶于水的 ON 013100 衍生物,具有靶作用于eIF4E对抗固体肿瘤的潜力。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Jasani, N., Desai, B.J., Betzu, J.M., et al.Abstract 1649: Potent anticancer activity of an orally bioavailable small molecule, ON 013100, and its water soluble derivative, briciclib, a clinical-stage eIF4E-targeted agentCancer Res.75(15 Suppl),1649(2015)