Briciclib
Cat. No.:YN280090
| 产品名称: | Briciclib |
| CAS No.: | 865783-99-9 |
| Chemical Name: | 2-methoxy-5-[[[(1E)-2-(2,4,6-trimethoxyphenyl)ethenyl]sulfonyl]methyl]-phenol 1-(dihydrogen phosphate) |
| Synonyms: | ON 014185 |
| 分子量: | 474.42 |
| 分子式: | C₁₉H₂₃O₁₀PS |
| SMILES: | O=S(CC1=CC(OP(O)(O)=O)=C(OC)C=C1)(/C=C/C2=C(OC)C=C(OC)C=C2OC)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Briciclib 是一种可溶于水的 ON 013100 衍生物,具有靶作用于eIF4E对抗固体肿瘤的潜力。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Jasani, N., Desai, B.J., Betzu, J.M., et al.Abstract 1649: Potent anticancer activity of an orally bioavailable small molecule, ON 013100, and its water soluble derivative, briciclib, a clinical-stage eIF4E-targeted agentCancer Res.75(15 Suppl),1649(2015)