Corosolic acid
Cat. No.：YN280126
CAS No. ：4547-24-4
| 产品名称: | Corosolic acid |
| CAS No.: | 4547-24-4 |
| Chemical Name: | 2α,3β-dihydroxy-urs-12-en-28-oic acid |
| Synonyms: | 科罗索酸; Colosolic acid |
| 分子量: | 472.70 |
| 分子式: | C₃₀H₄₈O₄ |
| SMILES: | O[C@H]1[C@H](O)C(C)(C)[C@@](CC[C@]2(C)[C@]3([H])CC=C4[C@@]2(C)CC[C@]5(C(O)=O)[C@@]4([H])[C@@H](C)[C@H](C)CC5)([H])[C@]3(C)C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Corosolic acid (Colosolic acid) 是一种天然化合物，据报道具有抗肿瘤活性。 |
| IC50和靶点: | |
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Ahn, K.-S., Hahm, M.S., Park, E.J., et al.Corosolic acid isolated from the fruit of Crataegus pinnatifida var. psilosa is a protein kinase C inhibitor as well as a cytotoxic agentPlanta Med.64(5),468-470(1998)
Banno, N., Akihisa, T., Tokuda, H., et al.Triterpene acids from the leaves of Perilla frutescens and their anti-inflammatory and antitumor-promoting effectsBiosci. Biotechnol. Biochem.68(1),85-90(2004)
Miura, T., Ueda, N., Yamada, K., et al.Antidiabetic effects of corosolic acid in KK-Ay diabetic miceBiol. Pharm. Bull.29(3),585-587(2006)
Yamaguchi, Y., Yamada, K., Yoshikawa, N., et al.Corosolic acid prevents oxidative stress, inflammation and hypertension in SHR/NDmcr-cp rats, a model of metabolic syndromeLife Sci.79(26),2474-2479(2006)
