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Eupatilin

Cat. No.:YN280139

  • CAS No. :22368-21-4

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    • 生物活性
    • 参考文献
    • 产品名称: Eupatilin
      CAS No.: 22368-21-4
      Chemical Name: 2-(3,4-dimethoxyphenyl)-5,7-dihydroxy-6-methoxy-4H-1-benzopyran-4-one
      Synonyms:异泽兰黄素
      分子量:344.32
      分子式:C₁₈H₁₆O₇
      SMILES:O=C1C=C(C2=CC=C(OC)C(OC)=C2)OC3=CC(O)=C(OC)C(O)=C13
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Eupatilin 是从蒿属植物中分到的亲脂性黄酮类化合物,是PPARα的激动剂,具有抗凋亡,抗氧化及抗炎等功效。
      IC50和靶点:
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      In Vivo:
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      Solvent & Solubility:
    • Shawi, A.A., Rasul, A., Khan, M., et al.Eupatilin: A flavonoid compound isolated from the artemisia plant, induces apoptosis and G2/M phase cell cycle arrest in human melanoma A375 cellsAfr. J. Pharm. Pharmacol.5(5),582-588(2011)

      Choi, Y., Jung, Y., and Kim, S.N.Identification of eupatilin from Artemisia argyi as a selective PPARα agonist using affinity selection ultrafiltration LC-MSMolecules20(8),13753-13763(2015)

      Koshihara, Y., Neichi, T., Murota, S.i., et al.Selective inhibition of 5-lipoxygenase by natural compounds isolated from Chinese plants, Artemisia rubripes NakaiFEBS Lett.158(1),41-44(1983)

      Liu, H., Hao, J., Wu, C., et al.Eupatilin alleviates lipopolysaccharide-induced acute lung injury by inhibiting inflammation and oxidative stressMed. Sci Monit.25,8289-8296(2019)

      Song, E.-H., Chung, K.-S., Kang, Y.-M., et al.Eupatilin suppresses the allergic inflammatory response in vitro and in vivoPhytomedicine42,1-8(2018)

      Choi, E.J., Oh, H.M., Na, B.R., et al.Eupatilin protects gastric epithelial cells from oxidative damage and down-regulates genes responsible for the cellular oxidative stressPharmacol. Res.25(6),1355-1364(2008)

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