Onjisaponin B
Cat. No.：YN280147
CAS No. ：35906-36-6
| 产品名称: | Onjisaponin B |
| CAS No.: | 35906-36-6 |
| Chemical Name: | (2β,3β,4α)-3-(β-D-glucopyranosyloxy)-2,27-dihydroxy-olean-12-ene-23,28-dioic acid, 28-[O-6-deoxy-α-L-mannopyranosyl-(1→3)-O-[O-β-D-galactopyranosyl-(1→4)-O-β-D-xylopyranosyl-(1→4)-6-deoxy-α-L-mannopyranosyl-(1→2)]-6-deoxy-4-O-[(2E)-3-(4-methoxyphenyl)-1-o |
| Synonyms: | 远志皂苷B |
| 分子量: | 1573.67 |
| 分子式: | C₇₅H₁₁₂O₃₅ |
| SMILES: | OC[C@](C1=CC[C@]2([H])[C@]3(C[C@H](O)[C@@H]4O[C@]([C@@H]([C@@H](O)[C@@H]5O)O)([H])O[C@@H]5CO)C)(CC[C@]6(C(O[C@H](O[C@H](C)[C@H](OC(/C=C/C7=CC=C(OC)C=C7)=O)[C@@H]8O[C@@](O[C@@H](C)[C@H](O)[C@H]9O)([H])[C@@H]9O)[C@@H]8O[C@@](O[C@@H](C)[C@H](O[C@@](OC[C@@H]( |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Onjisaponin B 是一种从远志中提取的天然产物。在 PC-12 细胞中，Onjisaponin B 能促进自噬，加速突变 α- 突触核蛋白和亨廷顿蛋白的降解，可用于帕金森病和亨廷顿病的研究。 |
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Li, C., Yang, J., Yu, S., et al.Triterpenoid saponins with neuroprotective effects from the roots of Polygala tenuifoliaPlanta Med.74(2),133-141(2008)
Li, X., Cui, J., Yu, Y., et al.Traditional Chinese nootropic medicine Radix Polygalae and Its active constituent Onjisaponin B reduce β-amyloid production and improve cognitive impairmentsPLoS One11(3),e0151147(1986)
Li, G., Yu, J., Zhang, L., et al.Onjisaponin B prevents cognitive impairment in a rat model of D-galactose-induced agingBiomed. Pharmacother.99,113-120(2018)
