Ginkgolide K
Cat. No.：YN280154
CAS No. ：153355-70-5
| 产品名称: | Ginkgolide K |
| CAS No.: | 153355-70-5 |
| Chemical Name: | (1R,3S,3aS,4R,6aR,7aS,10aR,11R,11aR)-3-(1,1-dimethylethyl)-2,3,10a,11-tetrahydro-4,11-dihydroxy-8-methyl-9H-1,7a-(epoxymethano)-1H,6aH-cyclopenta[c]furo[2,3-b]furo[3′,2′:3,4]cyclopenta[1,2-d]furan-5,9,12(4H)-trione |
| Synonyms: | 银杏内酯 K |
| 分子量: | 406.38 |
| 分子式: | C₂₀H₂₂O₉ |
| SMILES: | O[C@@H]([C@]1([H])O2)C34C5([C@H]6O)[C@](OC6=O)([H])O[C@@]3(C(O[C@]4([H])C[C@H]5C(C)(C)C)=O)C1=C(C)C2=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Ginkgolide K，可从Ginkgo biloba中分离得到，可通过AMPK/mTOR/ULK1信号通路诱导保护性自噬 (autophagy)。Ginkgolide K具有神经保护活性。 |
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van Beek, T.A.Ginkgolides and bilobalide: Their physical, chromatographic and spectroscopic propertiesBioorg. Med. Chem.13(17),5001-5012(2005)
Li, Q.-Y., Miao, Q., Sui, R.-X., et al.Ginkgolide K supports remyelination via induction of astrocytic IGF/PI3K/Nrf2 axisInt. Immunopharmacol.75,105819(2019)
Ma, S., Yin, H., Chen, L., et al.Neuroprotective effect of ginkgolide K against acute ischemic stroke on middle cerebral ischemia occlusion in ratsJ. Nat. Med.66(1),25-31(2012)
