LY367385
Cat. No.：YN320326
CAS No. ：198419-91-9
规格
价格(RMB)
库存
| 产品名称: | LY367385 |
| CAS No.: | 198419-91-9 |
| Chemical Name: | (S)-α-Amino-4-carboxy-2-methylbenzeneacetic Acid(S)-2-Methyl-4-carboxyphenylglycine; |
| Synonyms: | Benzeneacetic acid, a-amino-4-carboxy-2-methyl-, (aS)-;LY 367385;(R)-(+)-ALPHA-AMINO-4-CARBOXY-2-METHYLBENZENEACETIC ACID;AC1NSKBK;CHEBI:252690;CHEMBL94631;LY-367385;LY-367385 hydrochloride;PDSP1_001314;PDSP2_001298;SureCN661700;Tocris-1237;SGIKDIUCJAUSRD |
| 分子量: | 209.20 |
| 分子式: | C₁₀H₁₁NO₄ |
| SMILES: | OC([C@H](C1=C(C=C(C(O)=O)C=C1)C)N)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | LY367385 是一种高效且选择性的mGluR1a拮抗剂，抑制喹喹啉诱导的磷酸肌醇水解的IC50值为 8.8 μM，而对 mGlu5a 的IC50值大于 100 μM。LY367385 具有神经保护，抗惊厥和抗癫痫作用。 |
| IC50和靶点: | [{name:"mGluR1a:8.8 μM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Sulkowski, G. et al.: J. Neuroimmunol., 261, 67 (2013) & Yeganeh, F. et al.: J. Mol. Neurosci., 50, 551 (2013)
