(rac)-(trans)-Paroxetine-d
Cat. No.：YN280167
CAS No. ：1329809-23-5
| 产品名称: | (rac)-(trans)-Paroxetine-d |
| CAS No.: | 1329809-23-5 |
| Chemical Name: | N-[2-butyl-3-[4-[3-(dibutylamino)propoxy-1,1,2,2,3,3-d6]benzoyl]-5-benzofuranyl]-methanesulfonamide, monohydrochloride |
| Synonyms: | 决奈达隆 d |
| 分子量: | 599.25454 |
| 分子式: | C31H38D6N2O5S • HCl |
| SMILES: | CCCCC1=C(C(C2=CC=C(OC([2H])([2H])C([2H])([2H])C([2H])([2H])N(CCCC)CCCC)C=C2)=O)C3=CC(NS(C)(=O)=O)=CC=C3O1.Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Dronedarone-d6(hydrochloride) 是 Dronedarone 的氘代物。Dronedarone (SR 33589) hydrochloride 是胺碘酮 (HY-14187) 的衍生物，是一种用于研究心房颤动 (AF) 的 class III 抗心律失常的试剂 (antiarrhythmic agent)。Dronedarone hydrochloride 是多种离子电流 (ion currents) 的有效阻滞剂，包括钾电流，钠电流，和 L 型钙电流，并通过非竞争性结合到肾上 |
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Sun, W., Sarma, J.S., and Singh, B.N.Electrophysiological effects of dronedarone (SR33589), a noniodinated benzofuran derivative, in the rabbit heart: Comparison with amiodaroneCirculation100(22),2276-2281(1999)
Guillemare, E., Marion, A., Nisato, D., et al.Inhibitory effects of dronedarone on muscarinic K+ current in guinea pig atrial cellsJ. Cardiovasc. Pharmacol.36(6),802-805(2000)
Saengklub, N., Limprasutr, V., Sawangkoon, S., et al.Dronedarone attenuates the duration of atrial fibrillation in a dog model of sustained atrial fibrillationExp. Anim.66(3),251-258(2017)
