CZC-54252 hydrochloride
Cat. No.:YN280170
| 产品名称: | CZC-54252 hydrochloride |
| CAS No.: | 1784253-05-9 |
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| 分子量: | 541.45 |
| 分子式: | C22H26Cl2N6O4S |
| SMILES: | CS(=O)(NC1=CC=CC=C1NC2=NC(NC3=CC=C(N4CCOCC4)C=C3OC)=NC=C2Cl)=O.[H]Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | CZC-54252 hydrochloride 是一种有效的选择性LRRK2抑制剂,对野生型和G2019SLRRK2的IC50分别为 1.28 nM 和 1.85 nM。CZC-54252 hydrochloride 减弱由G2019SLRRK2诱导的人神经元损伤 ,EC50约为 1 nM,具有神经保护活性。 |
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