2-Methylthio-ATP tetrasodium
Cat. No.：YN480113
CAS No. ：100020-57-3
规格
价格(RMB)
库存
| 产品名称: | 2-Methylthio-ATP tetrasodium |
| CAS No.: | 100020-57-3 |
| Chemical Name: | 2-(methylthio)-adenosine 5'-(tetrahydrogen triphosphate), tetrasodium salt |
| Synonyms: | 2-Methylthioadenosine triphosphate tetrasodium salt,2-methylthio-atp-tetrasodium |
| 分子量: | 641.20 |
| 分子式: | C₁₁H₁₄N₅Na₄O₁₃P₃S |
| SMILES: | O[C@H]([C@@H]1O)[C@](O[C@@H]1CO[P](O[P](O[P](O[Na])(O[Na])=O)(O[Na])=O)(O[Na])=O)([H])N2C3=NC(SC)=NC(N)=C3N=C2 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | 2-Methylthio-ATP tetrasodium 是非特异性的P2-receptor的激动剂。2-Methylthio-ATP tetrasodium 引起 ADP 诱导的人血小板聚集的非竞争性抑制。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Pollatzek, E., Hitzel, N., Ott, D., et al.Functional expression of P2 purinoceptors in a primary neuroglial cell culture of the rat arcuate nucleusNeuroscience327,95-114(2016)
Schachter, J.B., and Harden, T.K.An examination of deoxyadenosine 5'(α-thio)triphosphate as a ligand to define P2Y receptors and its selectivity as a low potency partial agonist of the P2Y1 receptorBr. J. Pharmacol.121(2),338-334(1997)
Parkinson, S.J., Carrithers, S.L., and Waldman, S.A.Opposing adenine nucleotide-dependent pathways regulate guanylyl cyclase C in rat intestineJ. Biol. Chem.269(36),22683-22690(1994)
Zeng, C., Xia, T., Zheng, S., et al.Synergistic effect of uroguanylin and D1 dopamine receptors on sodium excretion in hypertensionJ. Am. Heart Assoc.11(6),e022827(2022)
