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CHIR-090

Cat. No.：728865-23-4

  • CAS No. ：728865-23-4

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    • 产品名称: CHIR-090
      CAS No.: 728865-23-4
      Chemical Name:
      Synonyms:CHIR090
      分子量:437.49
      分子式:C₂₄H₂₇N₃O₅
      SMILES:O=C(N[C@@H]([C@@H](C)O)C(NO)=O)C(C=C1)=CC=C1C#CC2=CC=C(CN3CCOCC3)C=C2
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
      Select Batch:
      Purity: 0.98
    • McClerren, A.L., Endsley, S., Bowman, J.L., et al.A slow, tight-binding inhibitor of the zinc-dependent deacetylase LpxC of lipid A biosynthesis with antibiotic activity comparable to ciprofloxacinBiochemistry44(50),16574-16583(2005)', 'Barb, A.W., McClerren, A.L., Snehelatha, K., et al.Inhibition of lipid A biosynthesis as the primary mechanism of CHIR-090 antibiotic activity in Escherichia coliBiochemistry46(12),3793-3802(2007)', 'Bodewits, K., Raetz, C.R., Govan, J.R., et al.Antimicrobial activity of CHIR-090, an inhibitor of lipopolysaccharide biosynthesis, against the Burkholderia cepacia complexAntimicrob. Agents Chemother.54(8),3531-3533(2010)
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