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Mevastatin

Cat. No.：73573-88-3

  • CAS No. ：73573-88-3

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    • 产品名称: Mevastatin
      CAS No.: 73573-88-3
      Chemical Name:
      Synonyms:美伐他汀; Compactin; ML236B
      分子量:390.51
      分子式:C₂₃H₃₄O₅
      SMILES:CC[C@H](C)C(O[C@H]1CCC=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(O3)=O)[C@@]12[H])=O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 0.98
    • Endo, A., Kuroda, M., and Tanzawa, K.Competitive inhibition of 3-hydroxy-3-methylglutaryl coenzyme A reductase by ML-236A and ML-236B fungal metabolites, having hypocholesterolemic activityFEBS Lett.72(2),323-326(1976)', 'Fears, R., Richards, D.H., and Ferres, H.The effect of compactin, a potent inhibitor of 3-hydroxy-3-methylglutaryl coenzyme-A reductase activity, on cholesterogenesis and serum cholesterol levels in rats and chicksAtherosclerosis.35(4),439-449(1980)', 'Ahn, K.S., Sethi, G., and Aggarwal, B.B.Reversal of chemoresistance and enhancement of apoptosis by statins through down-regulation of the NF-κB pathwayBiochem. Pharmacol.75(4),907-913(2008)', 'Conlon, M., Poltorack, C.D., Forcina, G.C., et al.A compendium of kinetic modulatory profiles identifies ferroptosis regulatorsNat. Chem. Biol.,(2021)', 'Endo, A.The discovery and development of HMG-CoA reductase inhibitorsJ. Lipid Res.33(11),1569-1582(1992)
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