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Bestatin

Cat. No.：58970-76-6

  • CAS No. ：58970-76-6

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    • 产品名称: Bestatin
      CAS No.: 58970-76-6
      Chemical Name:
      Synonyms:乌苯美司; Ubenimex
      分子量:308.37
      分子式:C₁₆H₂₄N₂O₄
      SMILES:CC(C)C[C@@H](C(O)=O)NC([C@@H](O)[C@H](N)CC1=CC=CC=C1)=O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 0.98
    • Umezawa, H., Ayoagi, T., Suda, H., et al.Bestatin, an inhibitor of aminopeptidase B, produced by actinomycetesJ. Antibiot. (Tokyo)29(1),97-99(1976)', 'Melzig, M.F., and Bormann, H.Betulinic acid inhibits aminopeptidase N activityPlanta Med.64(7),655-657(1998)', 'Örning, L., Krivi, G., and Fitzpatrick, F.A.Leukotriene A4 hydrolase. Inhibition by bestatin and intrinsic aminopeptidase activity establish its functional resemblance to metallohydrolase enzymesJ. Biol. Chem.266(3),1375-1378(1991)', 'Wang, X., Liu, Y., Liu, W., et al.Ubenimex, an APN inhibitor, could serve as an anti‑tumor drug in RT112 and 5637 cells by operating in an Akt‑associated mannerMol. Med. Rep.17(3),4531-4539(2018)', 'Zhao, S., Yao, K., Li, D., et al.Inhibition of LTA4H by bestatin in human and mouse colorectal cancerEBioMedicine44,361-374(2019)
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