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Brevianamide F

Cat. No.:YN250023

  • CAS No. :38136-70-8

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    • 生物活性
    • 参考文献
    • 产品名称: Brevianamide F
      CAS No.: 38136-70-8
      Chemical Name: (3S,8aS)-hexahydro-3-(1H-indol-3-ylmethyl)-pyrrolo[1,2-a]pyrazine-1,4-dione
      Synonyms:Cyclo(L-Pro-L-Trp)
      分子量:283.33
      分子式:C₁₆H₁₇N₃O₂
      SMILES:O=C(N[C@H]1CC2=CNC3=C2C=CC=C3)[C@@](CCC4)([H])N4C1=O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
      Select Batch:
      Purity: 98%
    • 产品描述: Brevianamide F (Cyclo(L-Pro-L-Trp)) 是从Colletotrichum gloeosporioides中分离得到的一种真菌毒素,具有抗菌活性。Brevianamide F 具有PI3Kα抑制活性,IC50值为 4.8 µM。
      IC50和靶点: [{name:"PI3Kα:4.8 μM (IC50)"}]
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Zhang, X.-Y., Xu, X.-Y., Peng, J., et al.Antifouling potentials of eight deep-sea-derived fungi from the South China SeaJ. Ind. Microbiol. Biotechnol.41(4),741-748(2014)

      Ben Ameur Mehdi, R., Shaaban, K.A., Rebai, I.K., et al.Five naturally bioactive molecules including two rhamnopyranoside derivatives isolated from the Streptomyces sp. strain TN58.Nat. Prod. Res.23(12),1095-1107(2009)

      Huang, P., Xie, F., Ren, B., et al.Anti-MRSA and anti-TB metabolites from marine-derived Verrucosispora sp. MS100047Appl. Microbiol. Biotechnol.100(17),7437-7447(2016)

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