Brevianamide F
Cat. No.:YN250023
CAS No. :38136-70-8
产品名称: | Brevianamide F |
CAS No.: | 38136-70-8 |
Chemical Name: | (3S,8aS)-hexahydro-3-(1H-indol-3-ylmethyl)-pyrrolo[1,2-a]pyrazine-1,4-dione |
Synonyms: | Cyclo(L-Pro-L-Trp) |
分子量: | 283.33 |
分子式: | C₁₆H₁₇N₃O₂ |
SMILES: | O=C(N[C@H]1CC2=CNC3=C2C=CC=C3)[C@@](CCC4)([H])N4C1=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Brevianamide F (Cyclo(L-Pro-L-Trp)) 是从Colletotrichum gloeosporioides中分离得到的一种真菌毒素,具有抗菌活性。Brevianamide F 具有PI3Kα抑制活性,IC50值为 4.8 µM。 |
IC50和靶点: | [{name:"PI3Kα:4.8 μM (IC50)"}] |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Zhang, X.-Y., Xu, X.-Y., Peng, J., et al.Antifouling potentials of eight deep-sea-derived fungi from the South China SeaJ. Ind. Microbiol. Biotechnol.41(4),741-748(2014)
Ben Ameur Mehdi, R., Shaaban, K.A., Rebai, I.K., et al.Five naturally bioactive molecules including two rhamnopyranoside derivatives isolated from the Streptomyces sp. strain TN58.Nat. Prod. Res.23(12),1095-1107(2009)
Huang, P., Xie, F., Ren, B., et al.Anti-MRSA and anti-TB metabolites from marine-derived Verrucosispora sp. MS100047Appl. Microbiol. Biotechnol.100(17),7437-7447(2016)