BM212
Cat. No.：YN250043
CAS No. ：146204-42-4
| 产品名称: | BM212 |
| CAS No.: | 146204-42-4 |
| Chemical Name: | 1-[[1,5-bis(4-chlorophenyl)-2-methyl-1H-pyrrol-3-yl]methyl]-4-methyl-piperazine |
| Synonyms: | Piperazine,1-[[1,5-bis(4-chlorophenyl)-2-methyl-1H-pyrrol-3-yl]methyl]-4-methyl-;BM-212;1-[[1,5-bis(4-chlorophenyl)-2-methylpyrrol-3-yl]methyl]-4-methylpiperazine;BM 212;BM 212 (bactericide);BM212 |
| 分子量: | 414.37 |
| 分子式: | C₂₃H₂₅Cl₂N₃ |
| SMILES: | CN1CCN(CC2=C(C)N(C3=CC=C(Cl)C=C3)C(C4=CC=C(Cl)C=C4)=C2)CC1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | BM212 是一种有效的分枝杆菌膜蛋白MmpL3抑制剂。BM212 对结核分枝杆菌和部分非结核分枝杆菌有较强的抑制活性。BM212 抗结核杆菌 H37Rv 菌株的 MIC 值为 5 µM。 |
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Deidda, D., Lampis, G., Fioravanti, R., et al.Bactericidal activities of the pyrrole derivative BM212 against multidrug-resistant and intramacrophagic Mycobacterium tuberculosis strainsAntimicrob. Agents Chemother.42(11),3035-3037(1998)
LaRosa, V., Poce, G., Canseco, J.O., et al.MmpL3 is the cellular target of the antitubercular pyrrole derivative BM212Antimicrob. Agents Chemother.56(1),324-331(2012)
