AAI101
Cat. No.:YN250088
| 产品名称: | AAI101 |
| CAS No.: | 1001404-83-6 |
| Chemical Name: | 3-[[(2S,3S,5R)-2-carboxy-3-methyl-4,4-dioxido-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-3-yl]methyl]-1-methyl-1H-1,2,3-triazolium, inner salt |
| Synonyms: | AAI101 |
| 分子量: | 314.32 |
| 分子式: | C₁₁H₁₄N₄O₅S |
| SMILES: | C[N+]1=NN(C[C@@](S([C@]2([H])C3)(=O)=O)(C)[C@H](C([O-])=O)N2C3=O)C=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | AAI101 是一种广谱的 β-lactamase 抑制剂,能够抵抗很多耐药革兰氏阴性细菌。 |
| IC50和靶点: | |
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Papp-Wallace, K.M., Bethel, C.R., Caillon, J., et al.Beyond piperacillin-tazobactam: Cefepime and AAI101 as a potent β-lactam-β-lactamase inhibitor combinationAntimicrob Agents Chemother.63(5),e00105-00119(2019)
Crandon, J.L., and Nicolau, D.P.In vitro activity of cefepime/AAI101 and comparators against cefepime non-susceptible EnterobacteriaceaePathogens4(3),620-625(2015)