Trovafloxacin mesylate
Cat. No.：YN250092
CAS No. ：147059-75-4
| 产品名称: | Trovafloxacin mesylate |
| CAS No.: | 147059-75-4 |
| Chemical Name: | 7-[(1α,5α,6α)-6-amino-3-azabicyclo[3.1.0]hex-3-yl]-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid, monomethanesulfonate |
| Synonyms: | 甲磺酸曲伐沙星 |
| 分子量: | 512.46 |
| 分子式: | C₂₁H₁₉F₃N₄O₆S |
| SMILES: | O=C(C1=CN(C2=CC=C(F)C=C2F)C3=NC(N4C[C@@]5([H])[C@H](N)[C@@]5([H])C4)=C(F)C=C3C1=O)O.CS(=O)(O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Trovafloxacin mesylate 是一种广谱喹诺酮类抗生素，对革兰氏阳性，革兰氏阴性和厌氧菌具有有效的活性。Trovafloxacin mesylate 可阻断 DNA 促旋酶 (DNA gyrase) 和拓扑异构酶 IV (topoisomerase IV) 的活性。Trovafloxacin mesylate 也是一种有效的，选择性的，口服活性的 Pannexin 1 通道 (PANX1) 抑制剂，对PANX1内向电流的IC50为 4 μM。Trovafloxacin mesylate 不 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Takei, M., Fukuda, H., Kishii, R., et al.Target preference of 15 quinolones against Staphylococcus aureus, based on antibacterial activities and target inhibitionAntimicrob. Agents Chemother.45(12),3544-3547(2001)
