Sutezolid
Cat. No.：YN250095
CAS No. ：168828-58-8
| 产品名称: | Sutezolid |
| CAS No.: | 168828-58-8 |
| Chemical Name: | N-[[(5S)-3-[3-fluoro-4-(4-thiomorpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]-acetamide |
| Synonyms: | PNU-100480; U-100480; PF-02341272 |
| 分子量: | 353.41 |
| 分子式: | C₁₆H₂₀FN₃O₃S |
| SMILES: | O=C(O[C@H]1CNC(C)=O)N(C1)C2=CC(F)=C(N3CCSCC3)C=C2 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Sutezolid (PNU-100480) 是一种具有口服活性恶唑烷酮抗菌剂，通过抑制细菌蛋白质合成发挥作用。Sutezolid 具有较强的抗分枝杆菌活性，用于耐药结核病的研究。 |
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Alffenaar, J.W., van der Laan, T., Simons, S., et al.Susceptibility of clinical Mycobacterium tuberculosis isolates to a potentially less toxic derivate of linezolid, PNU-100480Antimicrob. Agents Chemother.55(3),1287-1289(2011)
Zhang, M., Sala, C., Dhar, N., et al.In vitro and in vivo activities of three oxazolidinones against nonreplicating Mycobacterium tuberculosisAntimicrob. Agents Chemother.58(6),3217-3223(2014)
Loreto, E.S., Tondolo, J.S.M., Oliveira, D.C., et al.In vitro activities of miltefosine and antibacterial agents from the macrolide, oxazolidinone, and pleuromutilin classes against Pythium insidiosum and Pythium aphanidermatumAntimicrob. Agents Chemother.62(3),e01678-01617(2018)
