Azidamfenicol
Cat. No.：YN250116
| 产品名称: | Azidamfenicol |
| CAS No.: | 13838-08-9 |
| Chemical Name: | 2-azido-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]-acetamide |
| Synonyms: | |
| 分子量: | 295.25 |
| 分子式: | C₁₁H₁₃N₅O₅ |
| SMILES: | O=C(N[C@H](CO)[C@H](O)C1=CC=C([N+]([O-])=O)C=C1)CN=[N+]=[N-] |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Azidamfenicol 是一种广谱的氯霉素样抗生素。Azidamfenicol 可抑制核糖体肽基转移酶 (Ki=22 µM). |
| IC50和靶点: | |
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Poitschek, C., Thurner, J., and Haller, I.Determination of antimicrobial activity of a combination of azidoamphenicol, clotrimazole and dexamethasone in vitroArzneimittelforschung28(2),232-234(1978)
Bhuta, P., Chung, H.L., Hwang, J.-S., et al.Analogues of chloramphenicol: Circular dichroism spectra, inhibition of ribosomal peptidyltransferase, and possible mechanism of actionJ. Med. Chem.23(12),1299-1305(1980)
