Gamithromycin
Cat. No.：YN250159
CAS No. ：145435-72-9
| 产品名称: | Gamithromycin |
| CAS No.: | 145435-72-9 |
| Chemical Name: | (2R,3S,4R,5S,8R,10R,11R,12S,13S,14R)-13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-7-propyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-1-oxa-7-azacyclopentadec |
| Synonyms: | 加米霉素; ML-1709460 |
| 分子量: | 777.04 |
| 分子式: | C₄₀H₇₆N₂O₁₂ |
| SMILES: | O[C@H]([C@H](C[C@@H](C)O1)N(C)C)[C@]1([H])O[C@@H]2[C@H]([C@@H]([C@H](C(O[C@@H]([C@@](C)(O)[C@H](O)[C@@H](C)CN(CCC)[C@H](C)C[C@]2(O)C)CC)=O)C)O[C@@]3([H])C[C@](C)([C@@H](O)[C@H](C)O3)OC)C |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Gamithromycin 是一种可以抑制MmmSC菌株 B237 和 Tan8 生长的抗菌剂，MIC 值分别为 0.00012 和 0.00006 μg/mL。 |
| IC50和靶点: | |
| In Vitro: | |
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| Clinical Trial: | |
| Solvent & Solubility: |
Berghaus, L.J., Giguère, S., Sturgill, T.L., et al.Plasma pharmacokinetics, pulmonary distribution, and in vitro activity of gamithromycin in foalsJ. Vet. Pharmacol. Ther.35(1),59-66(2012)
Forbes, A.B., Ramage, C., Sales, J., et al.Determination of the duration of antibacterial efficacy following administration of gamithromycin using a bovine Mannheimia haemolytica challenge modelAntimicrob. Agents Chemother.55(2),831-835(2011)
Capik, S.F., White, B.J., Lubbers, B.V., et al.Comparison of the diagnostic performance of bacterial culture of nasopharyngeal swab and bronchoalveolar lavage fluid samples obtained from calves with bovine respiratory diseaseAm. J. Vet. Res.78(3),350-358(2017)
