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Clotrimazole

Cat. No.:YN250170

  • CAS No. :23593-75-1

    • 产品资料
    • 生物活性
    • 参考文献
    • 产品名称: Clotrimazole
      CAS No.: 23593-75-1
      Chemical Name: 1-[(2-chlorophenyl)diphenylmethyl]-1H-imidazole
      Synonyms:克霉唑
      分子量:344.84
      分子式:C₂₂H₁₇ClN₂
      SMILES:ClC1=CC=CC=C1C(N2C=CN=C2)(C3=CC=CC=C3)C4=CC=CC=C4
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
      Select Batch:
      Purity: 98%
    • 产品描述: Clotrimazole是咪唑衍生物,有抗真菌活性,是P450抑制剂。Clotrimazole 还具有抗菌活性。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Burgess, M.A., and Bodey, G.P.Clotrimazole (Bay b 5097): In vitro and clinical pharmacological studiesAntimicrob. Agents Chemother.2(6),423-426(1972)

      Shadomy, S.In vitro antifungal activity of clotrimazole (Bay b 5097)Infect. Immun.4(2),143-148(1971)

      Waitz, J.A., Moss, E.L., and Weinstein, M.J.Chemotherapeutic evaluation of clotrimazole [Bay b 5097, 1 (o-chloro-α-α-diphenylbenzyl) imidazole]Appl. Microbiol.22(5),891-898(1971)

      Fromtling, R.A.Overview of medically important antifungal azole derivativesClin. Microbiol. Rev.1(2),187-217(1988)

      Warrilow, A.G., Melo, N., Martel, C.M., et al.Expression, purification, and characterization of Aspergillus fumigatus sterol 14-a demethylase (CYP51) isoenzymes A and BAntimicrob. Agents Chemother.54(10),4225-4234(2010)

      Pegoraro, S., Lang, M., Dreker, T., et al.Inhibitors of potassium channels Kv1.3 and IK-1 as immunosuppressantsBioorg. Med. Chem. Lett.19(8),2299-2304(2009)

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