BPH-1358
Cat. No.：YN250275
CAS No. ：5352-53-4
| 产品名称: | BPH-1358 |
| CAS No.: | 5352-53-4 |
| Chemical Name: | N4,N4′-bis[3-(4,5-dihydro-1H-imidazol-2-yl)phenyl]-[1,1′-biphenyl]-4,4′-dicarboxamide |
| Synonyms: | NSC50460 |
| 分子量: | 601.53 |
| 分子式: | C₃₂H₃₀Cl₂N₆O₂ |
| SMILES: | O=C(C1=CC=C(C2=CC=C(C(NC3=CC=CC(C4=NCCN4)=C3)=O)C=C2)C=C1)NC5=CC=CC(C6=NCCN6)=C5.[H]Cl.[H]Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | BPH-1358 (NSC50460) 是一种有效的人FPPS和UPPS抑制剂，IC50值分别为 1.8 μM 和 110 nM，在体外对金黄色葡萄球菌的 MIC 值大约为 250 ng/mL。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Zhu, W., Wang, Y., Li, K., et al.Antibacterial drug leads: DNA and enzyme multitargetingJ. Med. Chem.58(3),1215-1227(2015)
Lindert, S., Zhu, W., Liu, Y.-L., et al.Farnesyl diphosphate synthase inhibitors from in silico screeningChem. Biol. Drug Des.81(6),742-748(2013)
