Psicofuranine
Cat. No.：YN250286
CAS No. ：1874-54-0
| 产品名称: | Psicofuranine |
| CAS No.: | 1874-54-0 |
| Chemical Name: | 1'-C-(hydroxymethyl)-adenosine |
| Synonyms: | |
| 分子量: | 297.27 |
| 分子式: | C₁₁H₁₅N₅O₅ |
| SMILES: | OC[C@@H]1[C@H]([C@H]([C@@](CO)(O1)N2C=NC3=C2N=CN=C3N)O)O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Psicofuramine 是一种核苷抗生素，具有抑制黄嘌呤 5'-磷酸氨化酶的作用。Psicofuramine 还可以特异性抑制GMP合酶，并中断寄生虫的生长。Psicofuramine 对恶性疟原虫的生长具有剂量依赖性抑制作用。 |
| IC50和靶点: | |
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Hanka, L.J.Mechanism of action of psicofuranineJ. Bacteriol.80,30-36(1960)
Udaka, S., and Moyed, H.S.Inhibition of parental and mutant xanthosine 5'-phosphate aminases by piscofuranineJ. Biol. Chem.238,2797-2803(1963)
Fukuyama, T.T.Formation of an adenyl xanthosine monophosphate intermediate by xanthosine 5'-phosphate aminase and its inhibition by psicofuranineJ. Biol. Chem.241(20),4745-4749(1966)
