Gossypetin
Cat. No.：YN250292
| 产品名称: | Gossypetin |
| CAS No.: | 489-35-0 |
| Chemical Name: | 2-(3,4-dihydroxyphenyl)-3,5,7,8-tetrahydroxy-4H-1-benzopyran-4-one |
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| 分子量: | 318.24 |
| 分子式: | C₁₅H₁₀O₈ |
| SMILES: | O=C1C(O)=C(OC2=C1C(O)=CC(O)=C2O)C3=CC(O)=C(C=C3)O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Gossypetin 是六羟基化的类黄酮，是一种有效的MKK3和MKK6抑制剂，可强烈减弱MKK3/6-p38信号传导途径，具有多种药理活性，包括抗氧化，抗菌和抗癌活性。 |
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Xie, X., Liu, K., Liu, F., et al.Gossypetin is a novel MKK3 and MKK6 inhibitor that suppresses esophageal cancer growth in vitro and in vivoCancer Lett.442,126-136(2019)
Chen, J.-H., Tsai, C.-W., Wang, C.-P., et al.Anti-atherosclerotic potential of gossypetin via inhibiting LDL oxidation and foam cell formationToxicol. Appl. Pharmacol.272(2),313-324(2013)
Lin, H.-H.In vitro and in vivo atheroprotective effects of gossypetin against endothelial cell injury by induction of autophagyChem. Res. Toxicol.28(2),202-215(2015)
