Qstatin
Cat. No.：YN250354
CAS No. ：902688-24-8
| 产品名称: | Qstatin |
| CAS No.: | 902688-24-8 |
| Chemical Name: | 1-[(5-bromo-2-thienyl)sulfonyl]-1H-pyrazole |
| Synonyms: | |
| 分子量: | 293.16 |
| 分子式: | C₇H₅BrN₂O₂S₂ |
| SMILES: | O=S(N1N=CC=C1)(C2=CC=C(Br)S2)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | QStatin 是一种有效且选择性的SmcR抑制剂 (V. harveyiLuxR 同源物)，EC50值为 208.9 nM，与 SmcR 紧密结合并改变了蛋白质的柔韧性，从而改变了其转录调控活性。QStatin 在多种弧菌中显示 pan-QS 抑制剂活性，并减弱其在水生宿主中的毒力。QStatin 可用于水产养殖的可持续性抗弧菌病药物。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Dorn, S.K., Newman, J.D., van Kessel, J.C., et al.Synthesis and biological assay of small-molecule quorum sensing inhibitors: A three-week course-based undergraduate research experienceJ. Chem. Educ.98(11),3533–3541(2021)
