Epetraborole hydrochloride
Cat. No.：YN250355
CAS No. ：1234563-16-6
| 产品名称: | Epetraborole hydrochloride |
| CAS No.: | 1234563-16-6 |
| Chemical Name: | 3-[[(3S)-3-(aminomethyl)-1,3-dihydro-1-hydroxy-2,1-benzoxaborol-7-yl]oxy]-1-propanol, monohydrochloride |
| Synonyms: | GSK2251052 hydrochloride |
| 分子量: | 273.52 |
| 分子式: | C₁₁H₁₇BClNO₄ |
| SMILES: | OCCCOC1=C(B(O)O[C@@H]2CN)C2=CC=C1.[H]Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Epetraborole hydrochloride (GSK2251052 hydrochloride) 是一个新颖的 LeuRS 抑制剂，能够通过绑定 leucyl-tRNA 合成酶终端的腺苷核糖抑制蛋白合成，可用于 Gram-negative 细菌引起的感染的研究。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Hernandez, V., Crépin, T., Palencia, A., et al.Discovery of a novel class of boron-based antibacterials with activity against gram-negative bacteriaAntimicrob. Agents and Chemother.57(3),1394-1403(2013)
