Nourseothricin sulfate
Cat. No.：YN250426
CAS No. ：96736-11-7
| 产品名称: | Nourseothricin sulfate |
| CAS No.: | 96736-11-7 |
| Chemical Name: | nourseothricin, monosulfate |
| Synonyms: | Streptothricin sulfate |
| 分子量: | 1359.47 |
| 分子式: | C₅₀H₉₄N₂₀O₂₂S |
| SMILES: | NC(O[C@H]1[C@@H](CO)O[C@@H](NC(N2)=N[C@]([C@@]2([H])[C@H](O)CN3)([H])C3=O)[C@H](NC(C[C@@H](N)CCCN(C(C[C@@H](N)CCCNC(C[C@@H](N)CCCN)=O)=O)[H])=O)[C@@H]1O)=O.O=S(O)(O)=O.NC(O[C@H]4[C@@H](CO)O[C@@H](NC(N5)=N[C@]([C@@]5([H])[C@H](O)CN6)([H])C6=O)[C@H](NC(C[C@ |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Nourseothricin sulfate (Streptothricin sulfate) 是一种广谱抗生素，可破坏革兰氏阴性菌的外膜，并且是Fonsecaea pedrosoi的主要选择性标记物。Nourseothricin sulfate 抑制原核细胞中蛋白质的生物合成，并强烈抑制真核生物如真菌的生长，还可作为细菌，酵母，丝状真菌和植物细胞等多种生物的选择性标记物。 |
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Shen, J., Guo, W., and Köhler, J.R.CaNAT1, a heterologous dominant selectable marker for transformation of Candida albicans and other pathogenic Candida speciesInfect. Immun.73(2),1239-1242(2005)
Kochupurakkal, B.S., and Iglehart, J.D.Nourseothricin N-acetyl transferase: A positive selection marker for mammalian cellsPLoS One8(7),e68509(2013)
Grammel, N., Pankevych, K., Demydchuk, J., et al.A β-lysine adenylating enzyme and a β-lysine binding protein involved in poly β-lysine chain assembly in nourseothricin synthesis in Streptomyces nourseiEur. J. Biochem.269(1),347-357(2002)
