Biapenem
Cat. No.:YN250495
CAS No. :120410-24-4
产品名称: | Biapenem |
CAS No.: | 120410-24-4 |
Chemical Name: | 6-[[(4R,5S,6S)-2-carboxy-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-en-3-yl]thio]-6,7-dihydro-5H-pyrazolo[1,2-a][1,2,4]triazol-4-ium, inner salt |
Synonyms: | 比阿培南; CLI 86815; L 627; LJC 10627 |
分子量: | 350.39 |
分子式: | C₁₅H₁₈N₄O₄S |
SMILES: | O=C1N2C(C([O-])=O)=C(SC(C3)CN4[N+]3=CN=C4)[C@H](C)[C@]2([H])[C@@]1([H])[C@H](O)C |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Biapenem (CLI 86815; L 627; LJC 10627) 是不经肠道的广谱碳青霉烯抗生素。 |
IC50和靶点: | |
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Hoban, D.J., Jones, R.N., Yamane, N., et al.In vitro activity of three carbapenem antibiotics. Comparative studies with biapenem (L-627), imipenem, and meropenem against aerobic pathogens isolated worldwideDiagn. Microbiol. Infect. Dis.17(4),299-305(1993)
Aldridge, K.E., Morice, N., and Schiro, D.D.In vitro activity of biapenem (L-627), a new carbapenem, against anaerobesAntimicrob. Agents Chemother.38(4),889-893(1994)
Kaushik, A., Ammerman, N.C., Tasneen, R., et al.In vitro and in vivo activity of biapenem against drug-susceptible and rifampicin-resistant Mycobacterium tuberculosisJ. Antimicrob. Chemother.72(8),2320-2325(2017)