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Biapenem

Cat. No.:YN250495

  • CAS No. :120410-24-4

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    • 生物活性
    • 参考文献
    • 产品名称: Biapenem
      CAS No.: 120410-24-4
      Chemical Name: 6-[[(4R,5S,6S)-2-carboxy-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-en-3-yl]thio]-6,7-dihydro-5H-pyrazolo[1,2-a][1,2,4]triazol-4-ium, inner salt
      Synonyms:比阿培南; CLI 86815; L 627; LJC 10627
      分子量:350.39
      分子式:C₁₅H₁₈N₄O₄S
      SMILES:O=C1N2C(C([O-])=O)=C(SC(C3)CN4[N+]3=CN=C4)[C@H](C)[C@]2([H])[C@@]1([H])[C@H](O)C
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
      Select Batch:
      Purity: 98%
    • 产品描述: Biapenem (CLI 86815; L 627; LJC 10627) 是不经肠道的广谱碳青霉烯抗生素。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Hoban, D.J., Jones, R.N., Yamane, N., et al.In vitro activity of three carbapenem antibiotics. Comparative studies with biapenem (L-627), imipenem, and meropenem against aerobic pathogens isolated worldwideDiagn. Microbiol. Infect. Dis.17(4),299-305(1993)

      Aldridge, K.E., Morice, N., and Schiro, D.D.In vitro activity of biapenem (L-627), a new carbapenem, against anaerobesAntimicrob. Agents Chemother.38(4),889-893(1994)

      Kaushik, A., Ammerman, N.C., Tasneen, R., et al.In vitro and in vivo activity of biapenem against drug-susceptible and rifampicin-resistant Mycobacterium tuberculosisJ. Antimicrob. Chemother.72(8),2320-2325(2017)

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