Delafloxacin meglumine
Cat. No.:YN250601
| 产品名称: | Delafloxacin meglumine | 
| CAS No.: | 352458-37-8 | 
| Chemical Name: | 1-deoxy-1-(methylamino)-D-glucitol, 1-(6-amino-3,5-difluoro-2-pyridinyl)-8-chloro-6-fluoro-1,4-dihydro-7-(3-hydroxy-1-azetidinyl)-4-oxo-3-quinolinecarboxylate (1:1) | 
| Synonyms: | 德拉沙星葡甲胺; ABT492 meglumine; RX-3341 meglumine; WQ-3034 meglumine | 
| 分子量: | 635.97 | 
| 分子式: | C₂₅H₂₉ClF₃N₅O₉ | 
| SMILES: | O=C(C1=CN(C2=NC(N)=C(F)C=C2F)C3=C(C=C(F)C(N4CC(O)C4)=C3Cl)C1=O)O.O[C@H]([C@H]([C@@H]([C@@H](CO)O)O)O)CNC | 
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. | 
| 运输: | Room temperature in continental US; may vary elsewhere. | 
| 产品描述: | Delafloxacin meglumine (ABT492 meglumine; RX-3341 meglumine; WQ-3034 meglumine) 是一种广谱氟喹诺酮类抗生素。Delafloxacin 具有广泛的活性,对耐药性的金黄色葡萄球菌,肺炎链球菌和肺炎克雷伯菌都有效。 | 
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Nilius, A.M., Shen, L.L., Hensey-Rudloff, D., et al.In vitro antibacterial potency and spectrum of ABT-492, a new fluoroquinoloneAntimicrob. Agents Chemother.47(10),3260-3269(2003)
Lepak, A.J., and Andes, D.R.In vivo pharmacodynamic target assessment of delafloxacin against Staphylococcus aureus, Streptococcus pneumoniae, and Klebsiella pneumoniae in a murine lung infection modelAntimicrob. Agents Chemother.60(8),4764-4769(2016)