TBA-7371
Cat. No.：YN250816
CAS No. ：1494675-86-3
规格
价格(RMB)
库存
| 产品名称: | TBA-7371 |
| CAS No.: | 1494675-86-3 |
| Chemical Name: | N-(2-hydroxyethyl)-1-[(6-methoxy-5-methyl-4-pyrimidinyl)methyl]-6-methyl-1H-pyrrolo[3,2-b]pyridine-3-carboxamide |
| Synonyms: | AZ 7371,DprE1-IN-1 |
| 分子量: | 355.39 |
| 分子式: | C₁₈H₂₁N₅O₃ |
| SMILES: | O=C(C1=CN(CC2=NC=NC(OC)=C2C)C3=CC(C)=CN=C31)NCCO |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | TBA-7371 是有效的，非共价的DprE1抑制剂。TBA-7371 具有强大的抗结核活性。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Chatterji, M., Shandil, R., Manjunatha, M.R., et al.1,4-azaindole, a potential drug candidate for treatment of tuberculosisAntimicrob. Agents Chemother.58(9),5325-5331(2014)
Shirude, P.S., Shandil, R., Sadler, C., et al.Azaindoles: Noncovalent DprE1 inhibitors from scaffold morphing efforts, kill Mycobacterium tuberculosis and are efficacious in vivoJ. Med. Chem.56(23),9701-9708(2013)
