Daptomycin
Cat. No.：YN250910
CAS No. ：103060-53-3
规格
价格(RMB)
库存
| 产品名称: | Daptomycin |
| CAS No.: | 103060-53-3 |
| Chemical Name: | 2,2'-((3S,6S,9R,15S,18R,21S,24S,30S,31R)-30-((S)-2-((R)-4-amino-2-((S)-2-decanamido-3-(1H-indol-3-yl)propanamido)-4-oxobutanamido)-3-carboxypropanamido)-3-(2-(2-aminophenyl)-2-oxoethyl)-24-(3-aminopropyl)-6-((R)-1-carboxypropan-2-yl)-9-(hydroxymethyl)-18, |
| Synonyms: | 达托霉素; LY146032 |
| 分子量: | 1620.67 |
| 分子式: | C₇₂H₁₀₁N₁₇O₂₆ |
| SMILES: | O=C(N[C@H](CC(N)=O)C(N[C@@H](CC(O)=O)C(N[C@H](C(NCC(N[C@H](C(N[C@@](C(N[C@@H](C(N[C@H]1CC(O)=O)=O)C)=O)([H])CC(O)=O)=O)CCCN)=O)=O)[C@H](OC([C@](NC([C@](NC([C@@](NC(CNC1=O)=O)([H])CO)=O)([H])[C@H](C)CC(O)=O)=O)([H])CC(C(C=CC=C2)=C2N)=O)=O)C)=O)=O)[C@@H](NC |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Daptomycin 是一种脂肽类抗生素，具有体外快速杀除革兰氏阳性细菌的活性。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Tally, F.P., and DeBruin, M.F.Development of daptomycin for Gram-positive infectionsJ. Antimicrob. Chemother.46(4),523-526(2000)
Steenbergen, J.N., Alder, J., Throne, G.M., et al.Daptomycin: A lipopeptide antibiotic for the treatment of serious Gram-positive infectionsJ. Antimicrob. Chemother.55(3),283-288(2005)
Pogliano, J., Pogliano, N., and Silverman, J.A.Daptomycin-mediated reorganization of membrane architecture causes mislocalization of essential cell division proteinsJ. Bacteriol.194(17),4494-4504(2012)
