Norfloxacin
Cat. No.:YN250920
产品名称: | Norfloxacin |
CAS No.: | 70458-96-7 |
Chemical Name: | 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid |
Synonyms: | 诺氟沙星; MK-0366 |
分子量: | 319.33 |
分子式: | C₁₆H₁₈FN₃O₃ |
SMILES: | O=C(C1=CN(CC)C2=C(C=C(F)C(N3CCNCC3)=C2)C1=O)O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Norfloxacin (MK-0366) 是广谱抗生素,能通过结合DNA旋转酶抑制革兰氏阳性和阴性菌。 |
IC50和靶点: | |
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Darrell, R.W., Modak, S.M., and Fox, C.L., Jr.Norfloxacin and silver norfloxacin in the treatment of Pseudomonas corneal ulcer in the rabbit.Trans. Am. Opthalmol. Soc.82,75-91(1984)
Awji, E.G., Damte, D., Lee, S.-J., et al.The in vitro activity of 15 antimicrobial agents against bacterial isolates from dogsJ. Vet. Med. Sci.74(8),1091-1094(2012)
Soriano, F., Rodriguez-Tudela, J.L., Castilla, C., et al.Treatment of encrusted cystitis caused by Corynebacterium group D2 with norfloxacin, ciprofloxacin, and teicoplanin in an experimental model in ratsAntimicrob. Agents Chemother.35(12),2587-2590(1991)