Pefloxacin mesylate dihydrate
Cat. No.:YN250928
CAS No. :149676-40-4
产品名称: | Pefloxacin mesylate dihydrate |
CAS No.: | 149676-40-4 |
Chemical Name: | 1-ethyl-6-fluoro-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid, monomethanesulfonate, dihydrate |
Synonyms: | 甲磺酸培氟沙星二水合物; Pefloxacinium mesylate dihydrate |
分子量: | 465.49 |
分子式: | C₁₈H₂₈FN₃O₈S |
SMILES: | O=C(C1=CN(CC)C2=C(C=C(F)C(N3CCN(C)CC3)=C2)C1=O)O.CS(=O)(O)=O.O.O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | 去水甲磺酸Pefloxacin是抗菌素,能通过抑制DNA旋转酶阻断细菌DNA复制。 |
IC50和靶点: | |
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Clarke, A.M., Zemcov, S.J., and Campbell, M.E.In-vitro activity of pefloxacin compared to enoxacin, norfloxacin, gentamicin and new β-lactamsJ. Antimicrob. Chemother.15(1),39-44(1985)
Jones, B.M., Geary, I., Lee, M.E., et al.Activity of pefloxacin and thirteen other antimicrobial agents in vitro against isolates from hospital and genitourinary infectionsJ. Antimicrob. Chemother.17(6),736-746(1986)
Tabary, X., Moreau, N., Dureuil, C., et al.Effect of DNA gyrase inhibitors pefloxacin, five other quinolones, novobiocin, and clorobiocin on Escherichia coli topoisomerase IAntimicrob. Agents Chemother.31(12),1925-1928(1987)
Fantin, B., Leggett, J., Ebert, S., et al.Correlation between in vitro and in vivo activity of antimicrobial agents against gram-negative bacilli in a murine infection modelAntimicrob. Agents Chemother.35(7),1413-1422(1991)