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Ceftazidime pentahydrate

Cat. No.:YN251104

  • CAS No. :78439-06-2

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    • 产品名称: Ceftazidime pentahydrate
      CAS No.: 78439-06-2
      Chemical Name: 1-[[(6R,7R)-7-[[(2Z)-(2-amino-4-thiazolyl)[(1-carboxy-1-methylethoxy)imino]acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-pyridinium, pentahydrate
      Synonyms:GR20263 pentahydrate
      分子量:636.65
      分子式:C₂₂H₃₂N₆O₁₂S₂
      SMILES:O=C1[C@@H](NC(/C(C2=CSC(N)=N2)=N\OC(C)(C(O)=O)C)=O)[C@@]3([H])SCC(C[N+]4=CC=CC=C4)=C(C([O-])=O)N13.[5H2O]
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
      Select Batch:
      Purity: 98%
    • 产品描述: Ceftazidime pentahydrate (GR20263 pentahydrate) 是第三代头孢菌素,可静脉内或肌肉给药。Ceftazidime pentahydrate 具有广泛的针对革兰氏阳性和革兰氏阴性需氧细菌的体外活性。Ceftazidime pentahydrate 对肠杆菌科 (包括 β-内酰胺酶阳性菌株) 特别有效,并且对大多数 β-内酰胺酶具有抗水解作用。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Acred, P., Ryan, D.M., Sowa, M.A., et al.The in-vivo antibacterial activity of ceftazidime (Gr 20263)—a comparison with other new β-lactam antibiotics and gentamicinJ. Antimicrob. Chemother.8(Suppl. B),247-255(1981)

      Fontana, R., Cornaglia, G., Ligozzi, M., et al.The final goal: Penicillin-binding proteins and the target of cephalosporinsClin. Microbiol. Infect.6(Suppl. 3),34-40(2000)

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