Dapsone
Cat. No.：YN251115
CAS No. ：80-08-0
| 产品名称: | Dapsone |
| CAS No.: | 80-08-0 |
| Chemical Name: | 4,4'-sulfonylbis-benzenamine |
| Synonyms: | 氨苯砜; 4,4′-Diaminodiphenyl sulfone; DDS |
| 分子量: | 248.30 |
| 分子式: | C₁₂H₁₂N₂O₂S |
| SMILES: | O=S(C1=CC=C(N)C=C1)(C2=CC=C(N)C=C2)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Dapsone (4,4′-Diaminodiphenyl sulfone; DDS) 是一种有效的血脑渗透和口服活性的抗生素 (antibiotic)，具有抑菌、抗细菌和抗原生动物活性。Dapsone 用于皮肤病疾病研究，如麻风病、疱疹样皮炎、寻常性痤疮等。 |
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Bonde, S.L., Bhadane, R.P., Gaikwad, A., et al.Simultaneous determination of dapsone and its major metabolite N-acetyl dapsone by LC-MS/MS methodInt. J. Pharm. Pharm. Sci.5(Suppl 3),441-446(2013)
Gijbels, M.J., Elliott, G.R., HogenEsch, H., et al.Therapeutic interventions in mice with chronic proliferative dermatitis (cpdm/cpdm)Exp. Dermatol.9(5),351-358(2000)
Diaz-Ruiz, A., Zavala, C., Montes, S., et al.Antioxidant, antiinflammatory and antiapoptotic effects of dapsone in a model of brain ischemia/reperfusion in ratsJ. Neurosci. Res.86(15),3410-3419(2008)
Holmes, I.B., and Hilson, G.R.The effect of rifampicin and dapsone on experimental Mycobacterium leprae infections: Minimum inhibitory concentrations and bactericidal actionJ. Med. Microbiol.5(2),251-261(1972)
Ramakrishnan, S.P., Basu, P.C., Singh, H., et al.Studies on the toxicity and action of diaminodiphenyl-sulfone (DDS) in avian and simian malariaBull. World Health Organ.27(2),213-221(1962)
