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Gemifloxacin mesylate

Cat. No.:YN251206

  • CAS No. :210353-53-0

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    • 产品名称: Gemifloxacin mesylate
      CAS No.: 210353-53-0
      Chemical Name: 7-[(4Z)-3-(aminomethyl)-4-(methoxyimino)-1-pyrrolidinyl]-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid, monomethanesulfonate
      Synonyms:甲磺酸吉米沙星; SB-265805S; LB-20304a
      分子量:485.49
      分子式:C₁₉H₂₄FN₅O₇S
      SMILES:O=C(C1=CN(C2CC2)C3=C(C=C(F)C(N4CC(CN)/C(C4)=N/OC)=N3)C1=O)O.CS(=O)(O)=O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Gemifloxacin mesylate 是一种口服的广谱喹诺酮类抗菌剂, 用于慢性支气管炎的急性细菌性发作, 及轻中度肺炎的研究。
      IC50和靶点:
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      In Vivo:
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      Solvent & Solubility:
    • Hammerschlag, M.R., Roblin, P.M., and Bébéar, C.M.Activity of telithromycin, a new ketolide antibacterial, against atypical and intracellular respiratory tract pathogensJ. Antimicrob. Chemother.48(Topic T1),25-31(2001)

      Ruiz-Serrano, M.J., Alcalá, L., Martínez, L., et al.In vitro activities of six fluoroquinolones against 250 clinical isolates of Mycobacterium tuberculosis susceptible or resistant to first-line antituberculosis drugsAntimicrob. Agents Chemother.44(9),2567-2568(2000)

      Collin, F., Karkare, S., and Maxwell, A.Exploiting bacterial DNA gyrase as a drug target: Current state and perspectivesAppl. Microbiol. Biotechnol.92(3),479-497(2011)

      Weigel, L.M., Anderson, G.J., and Tenover, F.C.DNA gyrase and topoisomerase IV mutations associated with fluoroquinolone resistance in Proteus mirabilisAntimicrob. Agents Chemother.46(8),2582-2587(2002)

      Grossman, R.F., Hsueh, P.-R., Gillespie, S.H., et al.Community-acquired pneumonia and tuberculosis: Differential diagnosis and the use of fluoroquinolonesInt. J. Infect. Dis.18,14-21(2014)

      Pranger, A.D., Alffenaar, J.W.C., and Aarnoutse, R.E.Fluoroquinolones, the cornerstone of treatment of drug-resistant tuberculosis: A pharmacokinetic and pharmacodynamic approachCurr. Pharm. Des.17(27),29002-29930(2011)

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