Chlorhexidine dihydrochloride
Cat. No.：YN251233
| 产品名称: | Chlorhexidine dihydrochloride |
| CAS No.: | 3697-42-5 |
| Chemical Name: | N1,N14-bis(4-chlorophenyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediimidamide, dihydrochloride |
| Synonyms: | 盐酸氯己定 |
| 分子量: | 578.37 |
| 分子式: | C₂₂H₃₂Cl₄N₁₀ |
| SMILES: | N=C(NC1=CC=C(Cl)C=C1)NC(NCCCCCCNC(NC(NC2=CC=C(Cl)C=C2)=N)=N)=N.[H]Cl.[H]Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Chlorhexidine二盐酸盐是一种抗菌剂， 用作防腐剂和其它用途。 |
| IC50和靶点: | |
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Karpiński, T.M., and Szkaradkiewicz, A.K.Chlorhexidine--Pharmaco-biological activity and applicationEur. Rev. Med. Pharmacol. Sci.19(7),1321-1326(2015)
McDanel, J.S., Murphy, C.R., Diekema, D.J., et al.Chlorhexidine and mupirocin susceptibilities of methicillin-resistant Staphylococcus aureus from colonized nursing home residentsAntimicrob. Agents Chemother.57(1),552-558(2013)
Clark, S.M., Loeffler, A., and Bond, R.Susceptibility in vitro of canine methicillin-resistant and -susceptible staphylococcal isolates to fusidic acid, chlorhexidine and miconazole: Opportunities for topical therapy of canine superficial pyodermaJ. Antimicrob. Chemother.70(7),2048-2052(2015)
Bhardwaj, P., Hans, A., Ruikar, K., et al.Reduced chlorhexidine and daptomycin susceptibility in vancomycin-resistant enterococcus faecium after serial chlorhexidine exposureAntimicrob. Agents Chemother.62(1),e01235-01217(2017)
Scheibler, E., da Silva, R.M., Leite, C.E., et al.Stability and efficacy of combined nystatin and chlorhexidine against suspensions and biofilms of Candida albicansArch. Oral Biol.89,70-76(2018)
Barrett-Bee, K., Newboult, L., and Edwards, S.The membrane destabilising action of the antibacterial agent chlorhexidineFEMS Microbiol. Lett.119(1-2),249-253(1994)
Gendron, R., Grenier, D., Sorsa, T., et al.Inhibition of the activities of matrix metalloproteinases 2, 8, and 9 by chlorhexidineClin. Diag. Lab. Immun.6(3),437-439(1999)
