Nitroxoline
Cat. No.：YN251244
CAS No. ：4008-48-4
| 产品名称: | Nitroxoline |
| CAS No.: | 4008-48-4 |
| Chemical Name: | 5-nitro-8-quinolinol |
| Synonyms: | 硝羟喹啉; 8-Hydroxy-5-nitroquinoline; 5-Nitro-8-quinolinol |
| 分子量: | 190.16 |
| 分子式: | C₉H₆N₂O₃ |
| SMILES: | OC1=C2N=CC=CC2=C([N+]([O-])=O)C=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Nitroxoline是一种抗生素, 有效防治生物膜感染, Nitroxoline通过从生物膜基质螯合Fe2+和Zn2+离子而发挥作用。 |
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Sobke, A., Makarewicz, O., Baier, M., et al.Empirical treatment of lower urinary tract infections in the face of spreading multidrug resistance: In vitro study on the effectiveness of nitroxolineInt. J. Antimicrob. Agents51(2),213-220(2018)
Abouelhassan, Y., Yang, Q., Yousaf, H., et al.Nitroxoline: A broad-spectrum biofilm-eradicating agent against pathogenic bacteriaInt. J. Antimicrob. Agents49(2),247-251(2017)
lazovic, J., Guo, L., Nakashima, J., et al.Nitroxoline induces apoptosis and slows glioma growth in vivoNeuro. Oncol.17(1),53-62(2015)
Jiang, H., Xing, J., Wang, C., et al.Discovery of novel BET inhibitors by drug repurposing of nitroxoline and its analoguesOrg. Biomol. Chem.15(44),9352-9361(2017)
