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Fusidic acid sodium salt

Cat. No.:YN251303

  • CAS No. :751-94-0

    • 产品资料
    • 生物活性
    • 参考文献
    • 产品名称: Fusidic acid sodium salt
      CAS No.: 751-94-0
      Chemical Name: (4α,8α,9β,13α,14β)-16β-(acetyloxy)- 3α,11α-dihydroxy-29-nordammara-17Z(20),24-dien-21-oic acid, monosodium salt
      Synonyms:夫西地酸钠; Sodium fusidate; SQ-16360
      分子量:538.69
      分子式:C₃₁H₄₇NaO₆
      SMILES:C[C@@H]([C@]1([H])CC[C@]([C@@](C[C@@H]/2OC(C)=O)3C)4C)[C@H](O)CC[C@]1(C)[C@]4([H])[C@H](O)C[C@@]3([H])C2=C(C(O[Na])=O)/CC/C=C(C)\C
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
      Select Batch:
      Purity: 98%
    • 产品描述: Fusidic acid sodium salt (Sodium fusidate),Fusidium coccineum属甾体类抑菌抗生素,无皮质类固醇作用。Fusidic acid sodium salt通过阻止核糖体释放翻译延长因子G (EF-G) 来抑制细菌的生长。
      IC50和靶点:
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      Solvent & Solubility:
    • Verbist, L.The antimicrobial activity of fusidic acidJ. Antimicrob. Chemother.25(Suppl. B),1-5(1990)

      Godtfredsen, W.O., Jahnsen, S., Lorck, H., et al.Fusidic acid: A new antibioticNature193,987(1962)

      Savelsbergh, A., Rodnina, M.V., and Wintermeyer, W.Distinct functions of elongation factor G in ribosome recycling and translocationRNA15(5),772-780(2009)

      Mohamed, M.F., and Seleem, M.N.Efficacy of short novel antimicrobial and anti-inflammatory peptides in a mouse model of methicillin-resistant Staphylococcus aureus (MRSA) skin infectionDrug Des. Devel. Ther.8,1979-1983(2014)

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