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Sulconazole mononitrate

Cat. No.:YN251324

  • CAS No. :61318-91-0

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    • 参考文献
    • 产品名称: Sulconazole mononitrate
      CAS No.: 61318-91-0
      Chemical Name: 1-[2-[[(4-chlorophenyl)methyl]thio]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole, mononitrate
      Synonyms:Exelderm,RS 44872
      分子量:460.76
      分子式:C₁₈H₁₆Cl₃N₃O₃S
      SMILES:[O-][N+](O)=O.ClC1=CC=C(C(SCC2=CC=C(Cl)C=C2)CN3C=CN=C3)C(Cl)=C1
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Sulconazole mononitrate ((±)-Sulconazole mononitrate) 是一种咪唑化合物,是广谱杀菌剂,对某些革兰氏阳性厌氧菌也有抑制作用。Sulconazole mononitrate 可以用于皮肤真菌病,花斑糠疹病,皮肤念珠菌病的研究。
      IC50和靶点:
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      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Odds, F.C., Webster, C.E., and Abbot, A.B.Antifungal relative inhibition factors: BAY 1–9139, bifonazole, butoconazole, isoconazole, itraconazole (R 51211), oxiconazole, Ro 14–4767/002, sulconazole, terconazole and vibunazole (BAY n-7133) compared in vitro with nine established antifungal agentsJ. Antimicrob. Chemother.14(2),105-114(1984)

      Hull, D.O., Bajrami, B., Jansson, I., et al.Characterizing metabolic inhibition using electrochemical enzyme/DNA biosensorsAnal. Chem.81(2),716-724(2009)

      Zhang, W., Ramamoorthy, Y., Kilicarslan, T., et al.Inhibition of cytochromes P450 by antifungal imidazole derivativesDrug Metab. Dispos.30(3),314-318(2002)

      Kinobe, R.T., Dercho, R.A., Vlahakis, J.Z., et al.Inhibition of the enzymatic activity of heme oxygenases by azole-based antifungal drugsJ. Pharmacol. Exp. Ther.319(1),277-284(2006)

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