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Kasugamycin hydrochloride

Cat. No.:YN251371

  • CAS No. :19408-46-9

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    • 参考文献
    • 产品名称: Kasugamycin hydrochloride
      CAS No.: 19408-46-9
      Chemical Name: 3-O-[2-amino-4-[(carboxyiminomethyl)amino]-2,3,4,6-tetradeoxy-α-D-arabino-hexopyranosyl]-D-chiro-inositol, monohydrochloride
      Synonyms:Ksg hydrochloride
      分子量:415.82
      分子式:C₁₄H₂₆ClN₃O₉
      SMILES:OC(C(N[C@@H](C[C@@H]1N)[C@@H](C)O[C@]1([H])O[C@@H]2[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)[C@H]2O)=N)=O.[H]Cl
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Kasugamycin hydrochloride (Ksg hydrochloride) 是一种既能结合 30s 和 70s 核糖体又不能结合 50s 亚基的抗生素。Kasugamycin hydrochloride (Ksg hydrochloride) 模拟 mRNA 核苷酸破坏 tRNA 结合并抑制典型翻译起始。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Hamada, M., Hashimoto, T., Takahashi, T., et al.Antimicrobial activity of kasugamycinJ. Antibiot. (Tokyo)18,104-106(1965)

      Uppala, S., and Zhou, X.G.Field efficacy of fungicides for management of sheath blight and narrow brown leaf spot of riceCrop Prot.104,72-77(2018)

      Lee, J.-H., Lee, C.-M., Lee, J.H., et al.Kasugamycin is a novel chitinase 1 inhibitor with strong antifibrotic effects on pulmonary fibrosisAm. J. Respir. Cell Mol. Biol.67(3),309-319(2022)

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