Kasugamycin hydrochloride
Cat. No.:YN251371
| 产品名称: | Kasugamycin hydrochloride | 
| CAS No.: | 19408-46-9 | 
| Chemical Name: | 3-O-[2-amino-4-[(carboxyiminomethyl)amino]-2,3,4,6-tetradeoxy-α-D-arabino-hexopyranosyl]-D-chiro-inositol, monohydrochloride | 
| Synonyms: | Ksg hydrochloride | 
| 分子量: | 415.82 | 
| 分子式: | C₁₄H₂₆ClN₃O₉ | 
| SMILES: | OC(C(N[C@@H](C[C@@H]1N)[C@@H](C)O[C@]1([H])O[C@@H]2[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)[C@H]2O)=N)=O.[H]Cl | 
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. | 
| 运输: | Room temperature in continental US; may vary elsewhere. | 
| 产品描述: | Kasugamycin hydrochloride (Ksg hydrochloride) 是一种既能结合 30s 和 70s 核糖体又不能结合 50s 亚基的抗生素。Kasugamycin hydrochloride (Ksg hydrochloride) 模拟 mRNA 核苷酸破坏 tRNA 结合并抑制典型翻译起始。 | 
| IC50和靶点: | |
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Hamada, M., Hashimoto, T., Takahashi, T., et al.Antimicrobial activity of kasugamycinJ. Antibiot. (Tokyo)18,104-106(1965)
Uppala, S., and Zhou, X.G.Field efficacy of fungicides for management of sheath blight and narrow brown leaf spot of riceCrop Prot.104,72-77(2018)
Lee, J.-H., Lee, C.-M., Lee, J.H., et al.Kasugamycin is a novel chitinase 1 inhibitor with strong antifibrotic effects on pulmonary fibrosisAm. J. Respir. Cell Mol. Biol.67(3),309-319(2022)