Josamycin
Cat. No.:YN251383
CAS No. :16846-24-5
产品名称: | Josamycin |
CAS No.: | 16846-24-5 |
Chemical Name: | 3-acetate 4B-(3-methylbutanoate) leucomycin V |
Synonyms: | 交沙霉素; EN-141 |
分子量: | 827.99 |
分子式: | C₄₂H₆₉NO₁₅ |
SMILES: | O[C@H]1[C@](O[C@H](C)[C@@H](O[C@@](O[C@@H](C)[C@@H]2OC(CC(C)C)=O)([H])C[C@]2(O)C)[C@@H]1N(C)C)([H])O[C@@H]([C@H](C[C@H]([C@H](/C=C/C=C/C3)O)C)CC=O)[C@H]([C@](CC(O[C@@H]3C)=O)([H])OC(C)=O)OC |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Josamycin (EN-141) 是一种大环内酯类抗生素,对多种病原体, 比如细菌 (bacteria) 具有抗菌活性。 Josamycin (EN-141) 对核糖体的解离常数Kd为 5.5 nM。 |
IC50和靶点: | |
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Solvent & Solubility: |
Osono, T., Oka, Y., Watanabe, S., et al.A new antibiotic, josamyicn. I. Isolation and physico-chemical characteristicsJ. Antibiot. (Tokyo)20(3),174-180(1967)
Reese, R.E., Betts, R.F., Goedde, L.W., et al.In vitro susceptibility of common clinical anaerobic and aerobic isolates against josamycinAntimicrob. Agents Chemother.10(2),253-257(1976)
Ono, T., Numata, K., Nagate, T., et al.In vitro and in vivo antibacterial activities of clarithromycinChemotherapy42(3),159-169(1996)