Morusin
Cat. No.:YN251505
产品名称: | Morusin |
CAS No.: | 62596-29-6 |
Chemical Name: | 2-(2,4-dihydroxyphenyl)-5-hydroxy-8,8-dimethyl-3-(3-methyl-2-buten-1-yl)-4H,8H-benzo[1,2-b:3,4-b′]dipyran-4-one |
Synonyms: | 桑辛素; Mulberrochromene |
分子量: | 420.45 |
分子式: | C₂₅H₂₄O₆ |
SMILES: | O=C1C2=C(O)C=C3C(C=CC(C)(C)O3)=C2OC(C4=CC=C(O)C=C4O)=C1C/C=C(C)\C |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Morusin是从M. australis分离的去乙烯基化黄酮,具有抗肿瘤,抗氧化,抗菌等各种生物活性。Morusin可抑制NF-κB和STAT3的活性。 |
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Shi, X., Yang, S., Zhang, G., et al.The different metabolism of morusin in various species and its potent inhibition against UDP-glucuronosyltransferase (UGT) and cytochrome p450 (CYP450) enzymesXenobiotica46(5),467-476(2016)
Jin, S.E., Ha, H., Shin, H.K., et al.Anti-allergic and anti-inflammatory effects of kuwanon G and morusin on MC/9 mast cells and HaCaT keratinocytesMolecules24(2),E265(2019)
Kang, S., Kim, E.O., Kim, S.H., et al.Morusin induces apoptosis by regulating expression of bax and survivin in human breast cancer cellsOncol. Lett.13(6),4558-4562(2017)
Nagle, A., Wu, T., Kuhen, K., et al.Imidazolopiperazines: Lead optimization of the second-generation antimalarial agentsJ. Med. Chem.55(9),4244-4273(2012)