Cyclosporin C
Cat. No.:YN251664
| 产品名称: | Cyclosporin C |
| CAS No.: | 59787-61-0 |
| Chemical Name: | 7-L-threonine-cyclosporin A |
| Synonyms: | Cyclosporin-C,Cs-C,CsC,环孢菌素 C |
| 分子量: | 1218.61 |
| 分子式: | C₆₂H₁₁₁N₁₁O₁₃ |
| SMILES: | O[C@@H]([C@](C(N[C@@](C(N(CC(N([C@H](C(N[C@H](C(N([C@H]1CC(C)C)C)=O)C(C)C)=O)CC(C)C)C)=O)C)=O)([H])[C@H](O)C)=O)([H])N(C([C@@H](N(C([C@@H](N(C([C@@H](N(C([C@H](NC([C@@H](NC1=O)C)=O)C)=O)C)CC(C)C)=O)C)CC(C)C)=O)C)C(C)C)=O)C)[C@H](C)C/C=C/C |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Cyclosporin C is a fungal metabolite that has been found inT. inflatumand has diverse biological activities, includingantifungal, antiviral, and immunosuppressant properties. Cyclosporin C is active against isolates ofB. cinerea,A. niger, andAlternaria,Mu |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
von Wartburg, A., and Traber, R.Cyclosporins, fungal metabolites with immunosuppressive activitiesProg. Med. Chem.25,1-33(1988)
Moussaïf, M., Jacques, P., Schaarwächter, P., et al.Cyclosporin C is the main antifungal compound produced by Acremonium luzulaeAppl. Environ. Microbiol.63(5),1739-1743(1997)
Damaso, C.R., and Moussatché, N.Inhibition of vaccinia virus replication by cyclosporin A analogues correlates with their affinity for cellular cyclophilinsJ. Gen. Virol.79(Pt 2),339-346(1998)
Sadeg, N., Pham-Huy, C., Rucay, P., et al.In vitro and in vivo comparative studies on immunosuppressive properties of cyclosporines A, C, D and metabolites M1, M17 and M21Immunopharmacol. Immunotoxicol.15(2-3),163-177(1993)